Genomics|Update|Current: CANCER

Genomics|Update|Current

Cancer

Ceritinib in ALK-rearranged non–small-cell lung cancer
Shaw A, et al. N Engl J Med 2014; 370:1189-1197March 27, 2014

Clinical applications of melanoma genetics 
Gabree M, et al. Curr Treat Options Oncol 2014 Mar

Clinical validation of the detection of KRAS and BRAFmutations from circulating tumor DNA
Alain R Thierry et al. Nature Medicine, March 23, 2014

Comparative genomic hybridisation array and DNA sequencing to direct treatment of metastatic breast cancer: a multicentre, prospective trial (SAFIR01/UNICANCER)
André F, et al. The Lancet Oncology, Volume 15, Issue 3, Pages 267 - 274, March 2014

Low response in metastatic breast cancer study despite precision approach shows real world challenge, Genome Web, Mar 25 [by free subscription only]

Comparing universal Lynch syndrome tumor-screening programs to evaluate associations between implementation strategies and patient follow-through 
Cragun D, et al. Genet Med 2014 Mar

Evaluation and correlation of risk recurrence in early breast cancer assessed by  Oncotype DX, clinicopathological markers and tumor cell dissemination in the blood and bone marrow 
Aktas B, et al. Mol Clin Oncol 2013 Nov;1(6):1049-54

Physicians' attitudes about multiplex tumor genomic testing
Gray SW, et al. J Clin Oncol 2014 Mar 24

Pretreatment selection of regimen according to genetic analysis improves the efficacy of chemotherapy in the first line treatment of metastatic colorectal cancer 
Kim do Y, et al. J Surg Oncol 2014 Mar;109(3):250-4