Phenomics: the next challenge. [Nat Rev Genet. 2010] - PubMed result

Nat Rev Genet. 2010 Dec;11(12):855-66.
Phenomics: the next challenge.

Houle D, Govindaraju DR, Omholt S.

Department of Biological Science, Florida State University, Tallahassee, Florida 32306-4295, USA. dhoule@bio.fsu.edu.

Abstract

A key goal of biology is to understand phenotypic characteristics, such as health, disease and evolutionary fitness. Phenotypic variation is produced through a complex web of interactions between genotype and environment, and such a 'genotype-phenotype' map is inaccessible without the detailed phenotypic data that allow these interactions to be studied. Despite this need, our ability to characterize phenomes - the full set of phenotypes of an individual - lags behind our ability to characterize genomes. Phenomics should be recognized and pursued as an independent discipline to enable the development and adoption of high-throughput and high-dimensional phenotyping.

PMID: 21085204 [PubMed - in process]
Phenomics: the next challenge. [Nat Rev Genet. 2010] - PubMed result